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The human brain is a mystery. But it’s increasingly clear that supporting the brain is key for overall health — while optimizing the brain may be the secret to getting the most out of life itself.
Nootropics may help. These natural or synthetic substances — also known as smart drugs, brain-boosters and memory-enhancers — are taken to help with recall, learning, mental energy, focus, mood and many other aspects of brain health and function.
It is often recommended that when you first take Adrafinil powder, you take a relatively small dose (e.g. 100mg) and work your way up gradually.
It is often recommended that when you first take Adrafinil powder, you take a relatively small dose (e.g. 100mg) and work your way up gradually. This way you will be able to monitor your response to each dose in detail, making it easier to work out which dose works best for you. It may be best to take each dosage for a week or two before moving up to the next amount.
dose spoon included - 10milligram
Whatever dose you opt for, sources state that you should not take Adrafinil daily, sticking to a maximum of two or three times a week at times when you need to feel alert.
Adrafinil is usually sold in 300mg doses when in capsule form. The majority of people recommend 300mg as a maximum dose, although some have reported taking up to 600mg on a regular basis.
Alza 36, a user on drugs-forum, describes his experience when taking just 50mg Adrafinil powder:
“About 30 minutes after dosing, I began to feel the onset; I felt maybe a little bit heavier, my eyes were open a little more, I felt as though I was obligated to pay attention to uninteresting things. 90 minutes into the experience, I began feeling what I believe its full effects. I had an increased awareness of what was going on around me, I felt very optimistic about everything, and I had almost God-like powers to think and concentrate. I felt very much awake … It is now six hours after the dose, and I am still feeling the plateau of this drug.”
Types of Nootropics
Many of the most popular nootropics overall are herbal, including Bacopa, Rhodiola and Ginkgo biloba. When herbal nootropics are “standardized,” their active ingredients — such as bacosides in Bacopa — are lab-isolated and presented in exact levels. Concentrated herbal extracts similarly enhance the potency of raw herbs, but are not as precise. Herbal nootropics are highly versatile, supporting brain function and mental performance in many ways.
Adaptogens are a sub-class of herbal nootropics that we separate for their unique anti-stress mechanisms of action. Adaptogens target the body’s endocrine system, where they neutralize stress hormones and stress responses. This helps the brain to “adapt” to all stressors; emotional, physical, toxic, environmental, etc.
Rhodiola rosea is an example of a nootropic that is both herbal and adaptogen in nature. By Benjamin Zwittnig [CC BY 2.5 si], via Wikimedia Commons
Here’s where things get a little more complicated, in terms of nootropic legality. In some cases, a nootropic compound that is found in plants may be synthesized in a laboratory, yielding a synthetic analogue of the original botanical. Two prominent examples are vinpocetine and huperzine-A. Because they walk the fine line between synthetic and botanical, in some countries they are regulated as drugs and you need a prescription to take them.
While nootropics are generally associated with over-the-counter supplements, they technically also include pharmaceutical drugs that have been prescribed by a doctor. Adderall and other pharmaceuticals are increasingly prescribed to help both children and adults who have attention problems. Nootropic drugs have an advantage of clinical proof in premarket testing, but also have notable disadvantages of side effects and addiction concerns.
Synthetic nootropics are somewhat controversial because they seem to have a lot in common with synthetic drugs, but are regulated differently in some parts of the world.
This class of nootropics originated in Russia in the 1960s, and now includes no less than 19 different brain-boosting compounds that all share a similar molecular structure. Piracetam may be the most well-known racetam nootropic. Although the United States FDA is not a fan of racetams, these compounds have for the most part been shown to be safe, well-tolerated and beneficial. Developed to both boost mental performance and assist with age-related cognitive decline, racetams appear to have far-reaching benefits for overall healthy brain function.
Phospholipids are a special types of fats that are associated with nootropic benefits and have important roles in brain cell formation. Some phospholipids taken for brain health include phosphatidylcholine, phosphatidylserine, Citicoline, Alpha-GPC, and DHA. Sourced from egg yolks, soy, sunflower, cold-water fish, and animal organs, phospholipids seem best suited for helping to build and repair brain cells. Some Play an especially important brain health role in supporting fluid, peak-performing brain cell membranes.
How do Nootropics Work?
Science doesn’t yet know exactly how nootropics work. But research has identified several different bio-activities by which nootropics might enhance brainpower.
The best nootropic compounds may promote several of these bio-activities at once. By combining nootropics into stacks, some supplements can effectively boost many aspects of cognition.
Research has suggested that nootropic nutrients appear to:
Enhance Brain Energy
The human brain is an energy-intensive organ, consuming about 20% of the body’s power supply.
When the brain doesn’t get the oxygen, circulation and nourishment it needs, its energy levels may decline — leading to brain fog, slow thinking and mental fatigue.
Nootropics can help brain energy metabolism by:
- Delivering more oxygen to brain cells that’s burned for energy
- Improving mitochondria efficiency and structural integrity
- Funneling fatty acids into brain cells to be burned as fuel
Better brain energy appears to translate to diverse mental performance enhancements, including improved brain energy, attention, processing speed and focus.